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Osteoporosis ICD-10 Codes - A Medical Coding Specialist’s 2025 Guide

A Professional discuss about the Osteoporosis with nurse and ICD-10 Codes.

Perfect osteoporosis ICD-10 coding is critical for claims accuracy, compensation, and compliance. With over 20% of claims denied due to medical coding errors, mastering these codes ensures your practice avoids costly setbacks. 

In this guide, I’ll break down the top osteoporosis ICD-10 codes, updated 2025 guidelines, and actionable fixes for common mistakes so you can code confidently.

What is Osteoporosis?

Osteoporosis is a medical condition caused by weakened bones, making them more liable to fractures. The disease often progresses noiselessly and painlessly until a fracture occurs, typically in the hip, spine, or wrist. Osteoporosis is more common in older adults, particularly postmenopausal women, but it can affect individuals of all ages and genders.

Why Osteoporosis ICD-10 Coding Matters

Osteoporosis affects 10 million+ Americans, making precise coding essential for:

  • Reimbursement for screenings, fractures, and treatments.
  • Contract with Medicare and private payer rules.
  • Accurate patient records for future care.

Pro Tip: Always pair ICD-10 codes with supporting documentation (e.g., bone density scans, fracture details) to avoid denials.

Top 10 Osteoporosis ICD-10 Codes (+ Use Cases)

M81.0 – Age-Related Osteoporosis without Fracture

  • When to Use: For patients with osteoporosis linked to aging, no current fracture.
  • Common Mistake: Confusing with M80.0 (osteoporosis with fracture).

M80.0 – Osteoporosis with Fracture, Unspecified Site

  • When to Use: For fragility fractures (e.g., wrist, hip) without site specificity.
  • Documentation Tip: Include fracture location if known (e.g., M80.08A for lumbar spine).

M80.8 – Other Osteoporosis with Fracture

  • When to Use: For fractures from secondary causes (e.g., steroid-induced).
  • Example: M80.8 + M85.8 for steroid-induced osteoporosis with vertebral fracture.

Z13.820 – Encounter for Osteoporosis Screening

  • When to Use: Routine DEXA scans for at-risk patients (e.g., postmenopausal women).
  • Medicare Rule: Covered every 24 months for eligible beneficiaries.

M85.8 – Other Specified Disorders of Bone Density

  • Once to Use: Osteopenia (low bone mass, not yet osteoporosis).
  • Key Detail: Link to risk factors (e.g., Z79.83 for long-term steroid use).
  • 8 – Other Osteoporosis Without Fracture
  • 310 – Personal History of Osteoporosis
  • 02 – Osteoporosis with Lumbar Fracture
  • 06 – Osteoporosis with Femoral Neck Fracture
  • A1 – Postmenopausal Osteoporosis

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2025 Osteoporosis Coding Guidelines

Specificity is Key                                                  

Avoid “unspecified” codes (e.g., M81.9) when possible. For example:

  • Use: M80.02 (lumbar fracture) instead of M80.0 (unspecified fracture).
  • Why: Payers like Medicare may deny M81.9 without clinical justification.

Linking Fractures to Osteoporosis

  • Always code the fracture first, followed by osteoporosis. For example:
  • S32.000A (vertebral fracture) + M80.08A (osteoporosis with lumbar fracture).

Screening vs. Diagnostic Codes

  • Screening: Z13.820 (asymptomatic patients).
  • Diagnostic: M81.0 or M80.0 (if fracture/abnormal findings).

3 Common Coding Mistakes (and Fixes)

  • Using Unspecified Codes Unnecessarily
    • Fix: Train staff to document fracture sites or secondary causes.
  • Mixing Screening and Diagnostic Codes
    • Fix: Confirm if the test was routine (Z13.820) or due to symptoms (M81.0).
  • Ignoring Laterality
    • Fix: Add 6th characters (e.g., M80.022A for left hip fracture).

Final Thoughts

Osteoporosis ICD-10 coding demands precision, whether you’re billing for screenings, fractures, or chronic care. By mastering codes like M80.0 and Z13.820, you’ll reduce denials and ensure compliance. 

Need help? Our team resolves coding errors in 48 hours. Schedule a Free Audit

Frequently Asked Questions (FAQs)

Use M80.8 (osteoporosis with fracture) or M81.8 (devoid of fracture) + T38.0X5A (contrary effect of glucocorticoids).

Code the fracture site (e.g., S22.000A for thoracic spine) + M80.08A (osteoporosis with pathological fracture).

Yes, for eligible patients (e.g., women over 65, estrogen-deficient patients) every 24 months.

Z82.62 (Family history of osteoporosis).

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