
The CPT code 85025 is used to report a Complete Blood Count (CBC) with Automated Differential. This test evaluates the overall health of a patientβs blood by measuring:
Healthcare providers order this test to:
When billing CPT code 85025, providers should be aware that it is often bundled with other codes, like:
If these tests are conducted simultaneously, insurance providers may need to bill them under a bundle code instead of individually. Failure to follow these rules can result in a decrease in claim denial or reimbursement.
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CPT Code |
Description |
Includes Differential? |
Typical Use |
Notes |
85025 |
Complete Blood Count (CBC) with automated differential WBC count |
Yes |
Detects anemia, infection, leukemia, and overall health monitoring |
Most commonly billed CBC code |
85027 |
CBC, automated, without differential |
No |
Basic blood health check without WBC breakdown |
Differential must be ordered separately |
85004 |
Automated differential WBC count only |
Yes |
Provides WBC breakdown when CBC without diff (85027) is performed |
Often paired with 85027 |
85018 |
Hemoglobin only |
No |
Screens for anemia or blood disorders |
Limited scope, not full CBC |
85014 |
Hematocrit only |
No |
Evaluates red blood cell volume |
Usually ordered with a hemoglobin test |
CPT 85025 is the most comprehensive single code because it includes a CBC plus differential, eliminating the need to bill multiple codes (like 85027 + 85004).
The CPT code 85025 plays an important role in healthcare by providing essential insights into a patientβs blood health. From detecting infections to monitoring chronic conditions, it remains one of the most frequently used and reimbursed lab codes. To avoid claim denials, providers should ensure accurate documentation, ICD-10 linkage, and correct billing practices.
Cures Medical Billing Services specializes in helping healthcare practices maximize reimbursements while staying compliant with 2025 coding guidelines. Contact us today to streamline your lab billing and reduce denials.
Yes. Itβs often billed alongside tests like 85018 (hemoglobin) or 80053 (comprehensive metabolic panel), but documentation must support medical necessity.
Frequency depends on medical necessity. For chronic conditions like anemia or chemotherapy monitoring, it may be billed multiple times a month. For preventive care, usually once per year.
Medicare and most private insurers cover it if linked to an appropriate ICD-10 diagnosis code (e.g., anemia, infection, abnormal labs).
Yes, but providers must ensure proper documentation. The lab test and the E/M visit can be reimbursed separately if billed correctly.
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