Osteoporosis ICD-10-CM Codes (2025) Complete Coding and Billing Guide

A Professional discuss about the Osteoporosis with nurse and ICD-10 Codes.

Key Takeaways

  • Osteoporosis ICD-10-CM codes are divided into M80 (with fracture) and M81 (without fracture).
  • Screening, personal history, and family history use Z codes.
  • Specificity—such as age-related, postmenopausal, or drug-induced- improves documentation accuracy.
  • Correct ICD-10 coding ensures better reimbursement and clinical record accuracy.

What is Osteoporosis?

Osteoporosis is a chronic bone condition characterized by the loss of bone mass and density, leading to fragile bones and an increased risk of fractures. Often called the silent disease, it progresses without symptoms until a fracture occurs.

Common risk factors include:

  • Aging and hormonal changes (especially menopause)
  • Family history of osteoporosis
  • Long-term steroid or drug use
  • Poor nutrition, smoking, or inactivity

Osteoporosis ICD-10-CM Codes Overview

Osteoporosis ICD-10-CM codes fall within categories M80–M82 of the 2025 edition of ICD-10-CM, effective on October 1, 2024, under the American ICD-10-CM version.
These billable specific ICD-10-CM codes are used for diagnosis and reimbursement purposes and distinguish between patients with and without current pathological fractures.

Osteoporosis without Current Pathological Fracture (M81 Series)

These codes apply when osteoporosis is diagnosed, but no active fracture is present:

  • M81.0: Age-related osteoporosis without current pathological fracture
  • M81.1: Postmenopausal osteoporosis without current pathological fracture
  • M81.2: Osteoporosis induced by drugs without current pathological fracture
  • M81.3: Idiopathic osteoporosis without current pathological fracture
  • M81.4: Osteoporosis due to endocrine disorders without current pathological fracture
  • M81.5: Osteoporosis secondary to other diseases without current pathological fracture
  • M81.6: Localized osteoporosis without current pathological fracture
  • M81.8: Other osteoporosis without current pathological fracture
  • M81.9: Osteoporosis, unspecified, without current pathological fracture

Each of these represents a billable specific ICD-10-CM diagnosis code valid in 2020, 2021, 2022, 2023, 2024, and 2025 editions.

Osteoporosis with Current Pathological Fracture (M80 Series)

These codes are used when the patient currently has a pathological fracture associated with osteoporosis:

  • M80.0: Age-related osteoporosis with current pathological fracture
  • M80.1: Postmenopausal osteoporosis with current pathological fracture
  • M80.2: Drug-induced osteoporosis with current pathological fracture
  • M80.3: Idiopathic osteoporosis with current pathological fracture
  • M80.4: Osteoporosis due to endocrine disorders with current pathological fracture
  • M80.5: Osteoporosis secondary to other diseases with current pathological fracture
  • M80.8: Other osteoporosis with current pathological fracture
  • M80.9: Osteoporosis, unspecified, with current pathological fracture

Note: When coding M80, also report the specific fracture site for complete documentation and proper linkage.

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Special Osteoporosis ICD-10 Codes

  • M82: Osteoporosis in diseases classified elsewhere
  • Z13.820: Encounter for screening for osteoporosis
  • Z87.310: Personal history of (healed) osteoporosis fracture
  • Z82.62: Family history of osteoporosis

These codes ensure proper clinical context and help with tracking preventive screenings and prior fracture events.

ICD-10 for Osteopenia (Related Condition)

Osteopenia refers to mild bone density loss that hasn’t yet progressed to osteoporosis.
Use:

  • M85.80 – M85.89 – Other specified disorders of bone density and structure (osteopenia).

These are also billable specific ICD-10-CM codes recognized under the 2025 edition of ICD-10-CM.

Coding Guidance and Type 2 Excludes Notes

Always review the Type 2 Excludes notes and context annotation back references in the ICD-10-CM manual. These notes indicate conditions that may occur simultaneously but are coded separately.
Such as, Osteoporosis with fracture (M80) and osteoporosis without fracture (M81) cannot be coded together for the same site.

Annotations and back references refer to codes within the same chapter for better cross-referencing and compliance.

Screening and History Codes

  • Screening for Osteoporosis:  Z13.820
  • Personal History of Osteoporosis: Z87.310
  • Family History of Osteoporosis: Z82.62

These codes apply to annotations and preventive encounters and are vital for Medicare and private payer coverage of bone density scans (DEXA tests).

Coding Tips for 2025

  • Always confirm whether a fracture is current or healed (M80 vs. M81).
  • Use the most specific code possible—such as postmenopausal or drug-induced.
  • For reimbursement purposes, include the correct diagnosis code that aligns with clinical documentation.
  • Update your EHR or billing software with the 2025 ICD-10-CM, effective on October 1, 2024.

Final Thoughts

Accurately coding osteoporosis ICD-10-CM diagnosis codes is key to ensuring proper documentation, reimbursement, and patient care continuity.
Whether reporting M81.0 for age-related osteoporosis or M80.x for osteoporosis with fractures, specificity ensures that claims are both clinically valid and financially compliant.

Partnering with Cures Medical Billing means:

  • Cleaner claims submission
  • Accurate ICD-10 coding updates
  • Reduced denials and faster payments

Let’s simplify coding, improve compliance, and maximize your reimbursement accuracy.

Frequently Asked Questions (FAQs)

Osteoporosis ICD-10 codes fall under M80–M81, depending on whether there is a current pathological fracture.

Osteoporosis without current pathological fracture is coded as M81.x, such as M81.0 for age-related osteoporosis.

Use M80 when the patient has a fracture due to bone loss and M81 when osteoporosis is present without a current fracture.

Osteoporosis with a current pathological fracture is coded as M80.x, such as M80.0 for age-related osteoporosis with fracture.

Key Z codes include Z13.820 (screening for osteoporosis), Z87.310 (personal history of osteoporosis fracture), and Z82.62 (family history of osteoporosis).

The correct code for screening is Z13.820.

Use Z87.310 for a personal history of healed osteoporosis fractures.

Postmenopausal osteoporosis is coded as M81.1 (without fracture) or M80.1 (with fracture).

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